MMA in Sows – Mastitis-Metritis-Agalactia Syndrome
Mastitis-metritis-agalactia syndrome (MMA) or post-partum dysgalactia syndrome (PPDS) is a disease of multiple aetiology and has close links with coliform mastitis and cystitis in sows. Multiple pathogens can be involved in the disease such as E.coli, Klebsiella spp., Enetrobacter spp., Mycoplasma spp. as well as Streptococci and Staphylococci. Other aetiological factors are related to endotoxins produced by, for example, E. coli, subclinical endometritis, retarded lactogenesis, hormonal imbalance, teat malformation and stress. Low fibre diet, fatness at farrowing and confinement have been found to be risk factors for sows.
MMA Syndrome can threaten the lives of both the sow and the piglets. MMA-syndrome occurs mostly within the first 48 hours after farrowing, but can also appear within the first week after farrowing.
MMA Syndrome requires rapid intervention to save the life and the future productivity of the sow as well as the lives of the piglets.
Due to its high efficacy and rapid bactericidal effect, Baytril® offers excellent therapeutic opportunities for MMA Syndrome. In different trials Baytril® was shown to be highly effective against the consequences of MMA Syndrome in metaphylactic as well as in therapeutic use.
In one study 828 sows were randomly divided in four groups which received the following:
Group 1 served as untreated controls
Group 2 received 25 g of a premix containing 1.25 g furazolidone, 5 g sulphadimidine, sodium sulphate and vitamins daily, given for three days before and after farrowing
Group 3 received 2.5 mg/kg bw Enrofloxacin (Baytril®) by i.m. injection immediately after farrowing.
Group 4 received 5 mg/kg bw Enrofloxacin (Baytril®) by i.m. injection immediately after farrowing.
The results showed a lower incidence of fever after farrowing, a lower incidence of elevated milk pH (above 6.7) and lower piglet mortality in the groups treated with Baytril®.
In another study the quick response to treatment with Baytril® was demonstrated.
Sows were divided randomly in two groups of 50 animals each.
Group 1 received Baytril® injectable solution in a dosage of 2.5 mg/kg bw i.m..
Group 2 received Baytril® like Group 1, while also receiving metamizole sodium at a dosage of 30 mg/kg bw.
The number of treatments that were required for full recovery was recorded. It was shown that the simultaneous application of an antipyretic/antiphlogistic drug had a beneficial effect on the recovery rate.
| 
