A clinical study (study outline) compared the efficacy of continuous and pulsed water medication with Baytril® 10% oral solution (enrofloxacin) or with two reference fluoroquinolones in chickens suffering from respiratory colibacillosis and septicemia.

Based on the efficacy criteria examined (mortality rate, degree of airsacculitis, clinical efficacy index) the results of this study showed that continuous and pulsed dosing were clinically equivalent. This finding emphasizes the flexibility of drinking water dosing with Baytril 10% oral solution in commercial poultry operations. Baytril® was more efficacious than both reference fluoroquinolones for the therapy of colisepticemia.

Charleston B. et al., 1998, Antimicrobial Agents and Chemotherapy 42:83-87